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Laparoscopic nerve lysis for deep endometriosis improves quality of life and chronic pain levels: A pilot study.
Cohen, Shlomo B; Dabi, Yohann; Burke, Yechiel; Mamadov, Nicole; Manoim, Nir; Mashiach, Roy; Berkowitz, Elad; Bouaziz, Jerome; Nicolas-Boluda, Alba; Grazia Porpora, Maria; Ziv-Baran, Tomer.
Affiliation
  • Cohen SB; Endometriosis and Chronic Pelvic Pain Unit, Department of obstetrics and gynecology, Sheba Medical Center, Ramat Gan, Israel and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
  • Dabi Y; Sorbonne University,Department of obstetrics and gynecology Tenon Hospital (AP-HP), Paris, France. Electronic address: yohann.dabi@gmail.com.
  • Burke Y; Endometriosis and Chronic Pelvic Pain Unit, Department of obstetrics and gynecology, Sheba Medical Center, Ramat Gan, Israel and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
  • Mamadov N; Endometriosis and Chronic Pelvic Pain Unit, Department of obstetrics and gynecology, Sheba Medical Center, Ramat Gan, Israel and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
  • Manoim N; Endometriosis and Chronic Pelvic Pain Unit, Department of obstetrics and gynecology, Sheba Medical Center, Ramat Gan, Israel and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
  • Mashiach R; Endometriosis and Chronic Pelvic Pain Unit, Department of obstetrics and gynecology, Sheba Medical Center, Ramat Gan, Israel and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
  • Berkowitz E; Endometriosis and Chronic Pelvic Pain Unit, Department of obstetrics and gynecology, Sheba Medical Center, Ramat Gan, Israel and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
  • Bouaziz J; Department of Research, One Clinic, 25 Boulevard Pasteur, 75015 Paris, France.
  • Nicolas-Boluda A; Department of Research, One Clinic, 25 Boulevard Pasteur, 75015 Paris, France.
  • Grazia Porpora M; Department of maternal and child health, Sapienza University, Rome, Italy.
  • Ziv-Baran T; Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
J Gynecol Obstet Hum Reprod ; 53(7): 102778, 2024 Apr 01.
Article in En | MEDLINE | ID: mdl-38570115
ABSTRACT

OBJECTIVES:

To assess the benefit of surgical management of patients with endometriosis infiltrating pelvic nerves in terms of pain, analgesic consumption, and quality of life (QOL).

METHODS:

We conducted a retrospective cohort study In an Endometriosis referral center at a tertiary care university affiliated medical center. Patients diagnosed with endometriosis that underwent laparoscopic neurolysis for chronic pain were included. Patients rated their pain before and after surgery and differentiated between chronic pain and acute crises. Patients were requested to maintain a record of analgesic consumption and to evaluate their quality-of-life (QOL).

RESULTS:

Of the 21 patients in our study 15 (71.5 %) had obturator nerve involvement, 2 (9.5 %) had pudendal nerve involvement and 4 (19 %) had other pelvic nerve involvement. Median postoperative follow - up was of 8 months. All but 2 patients (9.6 %) had significant chronic pain improvement with a mean decrease of VAS of 3.05 (±2.5). Analgesic habits changed postoperatively with a significant decrease of 66 % of patients' daily consumption of any analgesics. Surgery improved QOL in 12 cases (57.1 %) and two patients (9.6 %) completely recovered with a high QOL.

CONCLUSION:

Neurolysis and excision of endometriosis of pelvic nerves could results in significant improvement of quality of life.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Gynecol Obstet Hum Reprod Year: 2024 Document type: Article Affiliation country: Israel

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Gynecol Obstet Hum Reprod Year: 2024 Document type: Article Affiliation country: Israel