Quercetin alleviates hyperoxia-induced bronchopulmonary dysplasia by inhibiting ferroptosis through the MAPK/PTGS2 pathway: Insights from network pharmacology, molecular docking, and experimental evaluations.

Deng, Xianhui; Chen, Dan; Xie, Anni; Li, Shengpeng; Chen, Ailing; Zhou, Qin; Yu, Renqiang

Deng, Xianhui; Chen, Dan; Xie, Anni; Li, Shengpeng; Chen, Ailing; Zhou, Qin; Yu, Renqiang.

Affiliation

Deng X; Department of Neonatology, Affiliated Women's Hospital of Jiangnan University, Wuxi Maternity and Child Health Care Hospital, Wuxi, China.
Chen D; Department of Physiopathology, Wuxi School of Medicine, Jiangnan University, Wuxi, China.
Xie A; Department of Neonatology, Affiliated Women's Hospital of Jiangnan University, Wuxi Maternity and Child Health Care Hospital, Wuxi, China.
Li S; Department of Physiopathology, Wuxi School of Medicine, Jiangnan University, Wuxi, China.
Chen A; Research Institute for Reproductive Health and Genetic Diseases, Affiliated Women's Hospital of Jiangnan University, Wuxi, China.
Zhou Q; Department of Neonatology, Affiliated Women's Hospital of Jiangnan University, Wuxi Maternity and Child Health Care Hospital, Wuxi, China.
Yu R; Department of Pediatric, Wuxi Yihe Gynaecology and Obstetrics Hospital, Wuxi, China.

Chem Biol Drug Des ; 103(4): e14520, 2024 Apr.

Article in En | MEDLINE | ID: mdl-38570710

Subject(s)
Key words

PTGS2; bronchopulmonary dysplasia; ferroptosis; hyperoxia; quercetin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bronchopulmonary Dysplasia / Hyperoxia / Ferroptosis Limits: Animals / Humans / Newborn Language: En Journal: Chem Biol Drug Des Journal subject: BIOQUIMICA / FARMACIA / FARMACOLOGIA Year: 2024 Document type: Article Affiliation country: China Country of publication: Reino Unido

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