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The small molecule CBR-5884 inhibits the Candida albicans phosphatidylserine synthase.
Zhou, Yue; Phelps, Gregory A; Mangrum, Mikayla M; McLeish, Jemma; Phillips, Elise K; Lou, Jinchao; Ancajas, Christelle F; Rybak, Jeffrey M; Oelkers, Peter M; Lee, Richard E; Best, Michael D; Reynolds, Todd B.
Affiliation
  • Zhou Y; Department of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.
  • Phelps GA; Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Mangrum MM; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • McLeish J; Department of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.
  • Phillips EK; Department of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.
  • Lou J; Department of Microbiology, University of Tennessee, Knoxville, Tennessee, USA.
  • Ancajas CF; Department of Chemistry, University of Tennessee, Knoxville, Tennessee, USA.
  • Rybak JM; Department of Chemistry, University of Tennessee, Knoxville, Tennessee, USA.
  • Oelkers PM; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Lee RE; Department of Natural Sciences, University of Michigan-Dearborn, Dearborn, Michigan, USA.
  • Best MD; Department of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Reynolds TB; Department of Chemistry, University of Tennessee, Knoxville, Tennessee, USA.
mBio ; 15(5): e0063324, 2024 May 08.
Article in En | MEDLINE | ID: mdl-38587428
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida albicans / CDPdiacylglycerol-Serine O-Phosphatidyltransferase / Enzyme Inhibitors / Antifungal Agents Language: En Journal: MBio Year: 2024 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida albicans / CDPdiacylglycerol-Serine O-Phosphatidyltransferase / Enzyme Inhibitors / Antifungal Agents Language: En Journal: MBio Year: 2024 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos