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Elevated glucose promotes MMP13 and ADAMTS5 production by osteoarthritic chondrocytes under oxygenated but not hypoxic conditions.
Jain, Lekha; Bolam, Scott M; Monk, Paul; Munro, Jacob T; Tamatea, Jade; Dalbeth, Nicola; Poulsen, Raewyn C.
Affiliation
  • Jain L; Department of Pharmacology, University of Auckland, Auckland, New Zealand.
  • Bolam SM; Department of Surgery, University of Auckland, Auckland, New Zealand.
  • Monk P; Department of Surgery, University of Auckland, Auckland, New Zealand.
  • Munro JT; Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
  • Tamatea J; Department of Surgery, University of Auckland, Auckland, New Zealand.
  • Dalbeth N; Te Kupenga Hauora Maori, University of Auckland, Auckland, New Zealand.
  • Poulsen RC; Department of Medicine, University of Auckland, Auckland, New Zealand.
J Cell Physiol ; 239(6): e31271, 2024 Jun.
Article in En | MEDLINE | ID: mdl-38595042
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Cell Hypoxia / Chondrocytes / Matrix Metalloproteinase 13 / ADAMTS5 Protein / Glucose Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: J Cell Physiol Year: 2024 Document type: Article Affiliation country: Nueva Zelanda Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Cell Hypoxia / Chondrocytes / Matrix Metalloproteinase 13 / ADAMTS5 Protein / Glucose Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: J Cell Physiol Year: 2024 Document type: Article Affiliation country: Nueva Zelanda Country of publication: Estados Unidos