Porcine respiratory coronavirus genome sequences; comparisons and relationships to transmissible gastroenteritis viruses.
Virology
; 595: 110072, 2024 Jul.
Article
in En
| MEDLINE
| ID: mdl-38599031
ABSTRACT
Porcine respiratory coronavirus (PRCV) was initially detected in Europe, and later in the United States of America (US), in the 1980s. In this study we obtained and compared PRCV sequences from Europe and the US, and investigated how these are related to transmissible gastroenteritis virus (TGEV) sequences. The whole genome sequences of Danish (1/90-DK), Italian (PRCV15087/12 III NPTV Parma), and Belgian PRCV (91V44) strains are presented. These sequences were aligned with nine other PRCV sequences from Europe and the US, and 43 TGEV sequences. Following alignment of the PRCV sequences, it was apparent that multiple amino acid variations in the structural proteins were distinct between the European and US strains. The alignments were used to build phylogenetic trees to infer the evolutionary relationships between the strains. In these trees, the European PRCV strains clustered as a separate group, whereas the US strains of PRCV all clustered with TGEVs.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phylogeny
/
Swine Diseases
/
Genome, Viral
/
Transmissible gastroenteritis virus
Limits:
Animals
Country/Region as subject:
America do norte
/
Europa
Language:
En
Journal:
Virology
Year:
2024
Document type:
Article
Affiliation country:
Dinamarca
Country of publication:
Estados Unidos