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Assessment of dietary intake and its inflammatory potential in persons with pediatric-onset multiple sclerosis.
Bitarafan, Sama; Zhu, Feng; Mirza, Ali; Bernstein, Charles N; Van Domselaar, Gary; Marrie, Ruth Ann; Yeh, E Ann; Zhao, Yinshan; Banwell, Brenda; Waubant, Emmanuelle; Tremlett, Helen.
Affiliation
  • Bitarafan S; Faculty of Medicine (Neurology), University of British Columbia and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada; Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
  • Zhu F; Faculty of Medicine (Neurology), University of British Columbia and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.
  • Mirza A; Faculty of Medicine (Neurology), University of British Columbia and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.
  • Bernstein CN; Department of Internal Medicine and University of Manitoba IBD Clinical and Research Centre, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
  • Van Domselaar G; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada; Department of Medical Microbiology and Infectious Diseases, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
  • Marrie RA; Departments of Internal Medicine and Community Health Sciences, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
  • Yeh EA; Department of Pediatrics, Division of Neurology, The Hospital for Sick Children, Division of Neuroscience and Mental Health, SickKids Research Institute, University of Toronto, Toronto, Canada.
  • Zhao Y; Faculty of Medicine (Neurology), University of British Columbia and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.
  • Banwell B; Division of Child Neurology, Children's Hospital of Philadelphia, Departments of Neurology and Pediatrics, Perelman School of Medicine, University of Pennsylvania, USA.
  • Waubant E; Weill Institute for Neurosciences, Neurology Department, University of California, San Francisco, USA.
  • Tremlett H; Faculty of Medicine (Neurology), University of British Columbia and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada. Electronic address: helen.tremlett@ubc.ca.
Mult Scler Relat Disord ; 86: 105599, 2024 Jun.
Article in En | MEDLINE | ID: mdl-38604004
ABSTRACT

OBJECTIVE:

To compare diet and the modified dietary inflammatory index (mDII) between individuals with pediatric-onset multiple sclerosis (PoMS), monophasic acquired demyelinating syndromes (monoADS), and controls.

METHODS:

The association between diet, mDII, and disease status was examined in 131 individuals with PoMS/monoADS/controls (38/45/48) using logistic regression.

RESULTS:

The associations between diet and PoMS were modest, reaching significance for whole grain intake (adjusted odds ratio, aOR=0.964, 95 % confidence intervals, CI0.934-0.995) but not mDII (aOR=1.20, 95 %CI0.995-1.46) versus controls. No findings for monoADS reached significance versus controls.

CONCLUSIONS:

Individuals with PoMS, but not monoADS, had lower dietary whole grain intake than controls.
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Multiple Sclerosis Limits: Adolescent / Adult / Child / Female / Humans / Male Language: En Journal: Mult Scler Relat Disord Year: 2024 Document type: Article Affiliation country: Irán Publication country: HOLANDA / HOLLAND / NETHERLANDS / NL / PAISES BAJOS / THE NETHERLANDS

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Multiple Sclerosis Limits: Adolescent / Adult / Child / Female / Humans / Male Language: En Journal: Mult Scler Relat Disord Year: 2024 Document type: Article Affiliation country: Irán Publication country: HOLANDA / HOLLAND / NETHERLANDS / NL / PAISES BAJOS / THE NETHERLANDS