[The pharmacogenetics as integral part of personalized medicine: problems and prospects].
Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med
; 32(2): 173-179, 2024 Mar.
Article
in Ru
| MEDLINE
| ID: mdl-38640209
ABSTRACT
The article considers issues of implementation into clinical practice the principles of 5P medicine in its part of individualization of therapeutic tactics considering genetic characteristics of patients. The analysis of studies concerning influence of allelic variations on metabolism, safety and tolerance of the most often prescribed medicinal preparations was implemented. The main assumptions of pharmacogenomics were considered. Despite broad perspective of applying obtained data in clinical practice, there are a number of unresolved problems related to accessibility of genetic testing to population, ambiguity of approaches to interpretation of obtaining results, ethical issues and legal regulation.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pharmacogenetics
/
Precision Medicine
Limits:
Humans
Language:
Ru
Journal:
Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med
Journal subject:
SAUDE PUBLICA
Year:
2024
Document type:
Article
Country of publication:
Rusia