The cost implications of Wilson disease among hospitalized patients: analysis of USA hospitals.
Eur J Gastroenterol Hepatol
; 36(7): 929-940, 2024 Jul 01.
Article
in En
| MEDLINE
| ID: mdl-38652529
ABSTRACT
BACKGROUND AND AIM:
In this study, we used a national cohort of patients with Wilson's disease (WD) to investigate the admissions, mortality rates, and costs over the captured period to assess specific subpopulations at higher burden.METHODS:
Patients with WD were selected using 2016-2019 National Inpatient Sample (NIS). The weighted estimates and patient data were stratified using demographics and medical characteristics. Regression curves were graphed to derive goodness-of-fit for each trend from which R2 and P values were calculated.RESULTS:
Annual total admissions per 100â 000 hospitalizations due to WD were 1075, 1180, 1140, and 1330 ( R2 â =â 0.75; P â =â 0.13) from 2016 to 2019. Within the demographics, there was an increase in admissions among patients greater than 65 years of age ( R2 â =â 0.90; P â =â 0.05) and White patients ( R2 â =â 0.97; P â =â 0.02). Assessing WD-related mortality rates, there was an increase in the mortality rate among those in the first quartile of income ( R2 â =â 1.00; P â <â 0.001). The total cost for WD-related hospitalizations was $20.90, $27.23, $24.20, and $27.25 million US dollars for the years 2016, 2017, 2018, and 2019, respectively ( R2 â =â 0.47; P â =â 0.32). There was an increasing total cost trend for Asian or Pacific Islander patients ( R2 â =â 0.90; P â =â 0.05). Interestingly, patients with cirrhosis demonstrated a decreased trend in the total costs ( R2 â =â 0.97; P â =â 0.02).CONCLUSION:
Our study demonstrated that certain ethnicity groups, income classes and comorbidities had increased admissions or costs among patients admitted with WD.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Hospital Costs
/
Hepatolenticular Degeneration
/
Hospitalization
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
America do norte
Language:
En
Journal:
Eur J Gastroenterol Hepatol
Journal subject:
GASTROENTEROLOGIA
Year:
2024
Document type:
Article
Country of publication:
Reino Unido