Intellectual landscapes and emerging trends of non-steroidal mineralocorticoid receptor antagonists: a bibliometric and visual analysis.
Int Urol Nephrol
; 56(9): 3079-3090, 2024 Sep.
Article
in En
| MEDLINE
| ID: mdl-38662266
ABSTRACT
PURPOSE:
With increasing studies, non-steroidal mineralocorticoid receptor (MR) antagonists have been increasingly recognized as a major novel dimension in cardiorenal disease therapy. This bibliometric analysis aimed to uncover current research status and identify future research directions in the study of non-steroidal MR antagonists to inform subsequent investigations.METHODS:
Relevant English-language literature was retrieved from the Science Citation Index Expanded of the Web of Science Core Collection on January 10, 2024. Analyses of countries, institutions, authors, journals, documents, cited references and keywords were performed by the CiteSpace and VOSviewer software.RESULTS:
Overall, 498 documents, including 297 articles and 201 reviews, were included and analyzed. The United States (n = 188), Bayer AG (n = 78), and Professor Peter Kolkhof (n = 59) were the most prolific country, institution, and author in this field, respectively. Cluster analysis of cited references identified major clusters like cardiovascular disease, chronic kidney disease, and omecamtiv mecarbil. Keyword analysis indicated that sodium-glucose transport protein (SGLT)-2 inhibitors, pharmacotherapy, clinical trial, and guideline have emerged recently.CONCLUSION:
The field of non-steroidal MR antagonists is gradually gaining momentum as a novel pharmacotherapy in cardiorenal diseases, especially diabetic kidney disease, hypertension, and heart failure. Future studies will focus on add-on pharmacotherapy by combining non-steroidal MR antagonists with SGLT-2 inhibitors and the development and publication of clinical guidelines to facilitate patient management.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bibliometrics
/
Mineralocorticoid Receptor Antagonists
Limits:
Humans
Language:
En
Journal:
Int Urol Nephrol
/
Int. urol. nephrol
/
International urology and nephrology
Year:
2024
Document type:
Article
Affiliation country:
China
Country of publication:
Países Bajos