Visible-light-induced N-alkylation of anilines with 4-hydroxybutan-2-one.
RSC Adv
; 14(20): 14452-14455, 2024 Apr 25.
Article
in En
| MEDLINE
| ID: mdl-38694550
ABSTRACT
The synthesis of amines through N-alkylation is particularly attractive. Herein, a strategy for visible-light-induced N-alkylation of anilines with 4-hydroxybutan-2-one was developed in the presence of NH4Br, which avoid the use of metals, bases and ligands. In addition, gram-scale experiments proved that the system has the potential to be scaled.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
RSC Adv
Year:
2024
Document type:
Article