A scientific career from the early 1960s till 2023: A tale of the various protagonists.
Biochem Pharmacol
; : 116248, 2024 May 01.
Article
in En
| MEDLINE
| ID: mdl-38701868
ABSTRACT
In this era spanning more than 60 years (from the early 1960s till today (2023), a broad variety of actors played a decisive role Piet De Somer, Tom C. Merigan, Paul A. Janssen, Maurice Hilleman, and Georges Smets. Two protagonists (Antonín Holý and John C. Martin) formed with me a unique triangle (the Holý Trinity). Walter Fiers' group (with the help of Jean Content) contributed to the cloning of human ß-interferon, and Piet Herdewijn accomplished the chemical synthesis of an array of anti-HIV 2',3'-dideoxynucleoside analogues. Rudi Pauwels, Masanori Baba, Dominique Schols, Johan Neyts, Lieve Naesens, Anita Van Lierde, Graciela Andrei, Robert Snoeck and Dirk Daelemans, as members of my team, helped me in achieving the intended goal, the development of a selective therapy for virus infections. The collaboration with "Lowie" (Guangdi Li) generated a new dimension for the future.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Biochem Pharmacol
Year:
2024
Document type:
Article
Country of publication:
Reino Unido