Declining antibody affinity over time after human vaccination with a Plasmodium falciparum merozoite vaccine candidate.
J Infect Dis
; 2024 May 09.
Article
in En
| MEDLINE
| ID: mdl-38723177
ABSTRACT
Maintaining high affinity antibodies after vaccination may be important for long-lasting immunity to malaria, but data on induction and kinetics of affinity is lacking. In a Phase 1 malaria vaccine trial, antibody affinity increased following a second vaccination but declined substantially over 12-months, suggesting poor maintenance of high affinity antibodies.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
J Infect Dis
Year:
2024
Document type:
Article
Affiliation country:
Suecia