Anti-N-Methyl-D Receptor Encephalitis During Long-Term Adalimumab Therapy for Crohn's Disease.
ACG Case Rep J
; 11(5): e01360, 2024 May.
Article
in En
| MEDLINE
| ID: mdl-38725477
ABSTRACT
A 46-year-old woman with fistulizing Crohn's disease in clinical remission in the setting of long-term adalimumab therapy presented to hospital and was ultimately diagnosed with anti-N-methyl-D (NMDA) receptor antibody-mediated autoimmune encephalitis (NMDAr-AE). Inflammatory central nervous system and antibody-mediated adverse effects have been found to be associated with anti-tumor necrosis factor agents, with 5 previous case reports noting cases of NMDAr-AE in patients on these medications. The current article reports this case, which is unique for the length of adalimumab therapy before this presentation, as well as a summary of literature regarding anti-tumor necrosis factors and NMDAr-AE.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
ACG Case Rep J
Year:
2024
Document type:
Article
Affiliation country:
Canadá
Country of publication:
Estados Unidos