Autopsy report of a sudden infant death that was strongly suspicious of Kawasaki disease.
Pathol Int
; 74(7): 408-414, 2024 Jul.
Article
in En
| MEDLINE
| ID: mdl-38751008
ABSTRACT
We conducted an autopsy on a 3-month-old boy in whom Kawasaki disease (KD) was strongly suspected based on the autopsy findings. The infant had a fever and was brought to a nearby clinic, where he was prescribed antipyretics and kept under observation. However, 15 days after onset of the fever, he suddenly died in bed. He exhibited no obvious redness of the lips, tongue, or conjunctiva. Membranous desquamation was present on his distal fingers. Vasculitis was observed in the coronary arteries, renal artery, splenic artery, and pulmonary vein. In addition, coronary artery aneurysms were present in the right coronary artery and left anterior descending artery. Thrombotic occlusion was observed in one aneurysm in the right coronary artery, resulting in acute myocardial infarction. The coronary artery wall showed infiltration of numerous macrophages and neutrophils. This case was classified as incomplete KD because the coronary artery aneurysm could not be demonstrated before death and was only recognized at autopsy. Pathologists and forensic scientists need to be aware that there are cases in which KD goes undiagnosed and untreated, leading to coronary artery aneurysm formation and sudden death.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Autopsy
/
Sudden Infant Death
/
Mucocutaneous Lymph Node Syndrome
Limits:
Humans
/
Infant
/
Male
Language:
En
Journal:
Pathol Int
/
Pathol. int
/
Pathology international
Journal subject:
PATOLOGIA
Year:
2024
Document type:
Article
Affiliation country:
Japón
Country of publication:
Australia