Chemical constituents from the leaves and branches of Wikstroemia chamaedaphne with their activation of latent HIV activities.
J Asian Nat Prod Res
; 26(10): 1239-1246, 2024 Oct.
Article
in En
| MEDLINE
| ID: mdl-38780916
ABSTRACT
A new compound, named coniferin B (1), and fourteen known compounds were purified and identified from the leaves and branches of Wikstroemia chamaedaphne Meisn. Their chemical structures were elucidated through analyzing spectroscopic and HRESIMS data. Compounds 2, 3, 5, 7-9, 11, and 13 were isolated from this plant for the first time. All compounds were assayed for cytotoxicity and activation of latent HIV activity on NH2 cells. The results showed that all compounds did not produce cytotoxicity at 10.0 µM and compounds 1, 9-11 showed weak activating activity with activation folds of 4.88, 7.14, 5.3, and 6.97, respectively.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Plant Leaves
/
Wikstroemia
Limits:
Humans
Language:
En
Journal:
J Asian Nat Prod Res
/
J. Asian nat. prod. res. (Online)
/
Journal of Asian natural products research (Online)
Journal subject:
BOTANICA
/
QUIMICA
Year:
2024
Document type:
Article
Affiliation country:
China
Country of publication:
Reino Unido