Indian consensus on the managemeNt of carbapenem-resistant enterobacterales infection in critically ill patients II (ICONIC II).
Expert Rev Anti Infect Ther
; 22(6): 453-468, 2024 Jun.
Article
in En
| MEDLINE
| ID: mdl-38790080
ABSTRACT
INTRODUCTION:
The rising challenge of carbapenem-resistant Enterobacterales (CRE) infections in Indian healthcare settings calls for clear clinical guidance on the management of these infections. The Indian consensus on the management of CRE infection in critically ill patients (ICONIC-II) is a follow-up of the ICONIC-I study, which was undertaken in 2019. AREAS COVERED A modified Delphi method was used to build expert consensus on CRE management in India, involving online surveys, face-to - face expert meetings, and a literature review. A panel of 12 experts was formed to develop potential clinical consensus statements (CCSs), which were rated through two survey rounds. The CCSs were finalized in a final face-to - face discussion. The finalized CCSs were categorized as consensus, near consensus, and no consensus. EXPERT OPINION The outcomes included 46 CCSs (consensus 40; near consensus 3; and no consensus 3). The expert panel discussed and achieved consensus on various strategies for managing CRE infections, emphasizing the significance of existing and emerging resistance mechanisms, prompt and tailored empiric therapy, and use of combination therapies. The consensus statements based on the collective expertise of the panel can potentially assist clinicians in the management of CRE infections that lack high-level evidence.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Delphi Technique
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Critical Illness
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Consensus
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Enterobacteriaceae Infections
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Carbapenem-Resistant Enterobacteriaceae
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Anti-Bacterial Agents
Limits:
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
Expert Rev Anti Infect Ther
Journal subject:
DOENCAS TRANSMISSIVEIS
Year:
2024
Document type:
Article
Affiliation country:
India