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A Comprehensive Look at the Development of Asthma in Children.
Diaconu, Ileana Diana; Gheorman, Veronica; Grigorie, Gabriela Adriana; Gheonea, Cristian; Tenea-Cojan, Tiberiu-Stefanita; Mahler, Beatrice; Voropanov, Ion Alexandru; Firoiu, Mihnea Cristian; Pîrvu, Andreea Silvia; Popescu, Alexandru Bogdan; Varuț, Renata.
Affiliation
  • Diaconu ID; Department of Pediatric Pneumology, University of Medicine and Pharmacy of Craiova, Petru Rareș 2 Str., 200349 Craiova, Romania.
  • Gheorman V; Department of Medical Semiology, University of Medicine and Pharmacy of Craiova, Petru Rareș 2 Str., 200349 Craiova, Romania.
  • Grigorie GA; Department of Pneumology, University of Medicine and Pharmacy of Craiova, Petru Rareș 2 Str., 200349 Craiova, Romania.
  • Gheonea C; Department of Pediatrics, University of Medicine and Pharmacy of Craiova, Petru Rareș 2 Str., 200349 Craiova, Romania.
  • Tenea-Cojan TS; Department of Surgery, University of Medicine and Pharmacy of Craiova, CFR Hospital of Craiova, Stirbei-Voda Str., 200374 Craiova, Romania.
  • Mahler B; Department of Pneumology, Faculty of Medicine "Carol Davila", "Marius Nasta" Institute of Pneumoftiziology, 050159 Bucharest, Romania.
  • Voropanov IA; Department of Pediatric Pneumology, Carol Davila University of Medicine and Pharmacy, "Marius Nasta" Institute of Pneumoftiziology, 050159 Bucharest, Romania.
  • Firoiu MC; Department of Urology, Fundeni Clinical Institute, Carol Davila University of Medicine and Pharmacy, Sos. Fundeni nr. 258, 022328 Bucharest, Romania.
  • Pîrvu AS; Department of Biochemistry, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
  • Popescu AB; Radiology Department, Targoviste County Emergency Hospital, Tudor Vladimirescu 48 Str., 130083 Targoviste, Romania.
  • Varuț R; Department of Pharmacology, University of Medicine and Pharmacy, Petru Rares Street 2-4, 200349 Craiova, Romania.
Children (Basel) ; 11(5)2024 May 11.
Article in En | MEDLINE | ID: mdl-38790577
ABSTRACT
Asthma, a prevalent chronic respiratory condition affecting millions of children globally, presents a significant health challenge. This review critically examines the developmental pathways of asthma in children, focusing on genetic, environmental, and early-life determinants. Specifically, we explore the impact of prenatal and postnatal factors such as maternal smoking, nutrition, respiratory infections, and allergen exposure on asthma development. Our analysis highlights the intricate interplay of these influences and their contribution to childhood asthma. Moreover, we emphasize targeted strategies and interventions to mitigate its burden, including genetic counseling for at-risk families, environmental modifications to reduce triggers, and early-life immunomodulation. By delving into these preventive measures and interventions, our review aims to provide actionable insights for healthcare professionals in developing tailored strategies to address the complexities of childhood asthma. In summary, this article offers a detailed examination of asthma development in children, aiming to enhance understanding and inform efforts to reduce its burden through targeted interventions.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Children (Basel) Year: 2024 Document type: Article Affiliation country: Rumanía Country of publication: Suiza

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Children (Basel) Year: 2024 Document type: Article Affiliation country: Rumanía Country of publication: Suiza