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Gastrointestinal amyloidosis in a 50-year-old patient with miliary tuberculosis: A case report.
Rauf, Sameer Abdul; Shah, Hussain Haider; Khatri, Rahul; Ul Haq, Mansoor; Dave, Tirth; Ali, Javaria Parwez; Ali, Syed Khizar.
Affiliation
  • Rauf SA; Department of Internal Medicine Liaquat National Hospital and Medical College Karachi Pakistan.
  • Shah HH; Department of Internal Medicine Dow University of Health Sciences Karachi Pakistan.
  • Khatri R; Department of Internal Medicine Liaquat National Hospital and Medical College Karachi Pakistan.
  • Ul Haq M; Department of Gastroenterology Liaquat National Hospital and Medical College Karachi Pakistan.
  • Dave T; Bukovinian State Medical University Chernivtsi Ukraine.
  • Ali JP; Department of Histopathology Liaquat National Hospital and Medical College Karachi Pakistan.
  • Ali SK; Department of Internal Medicine Liaquat National Hospital and Medical College Karachi Pakistan.
Clin Case Rep ; 12(6): e8978, 2024 Jun.
Article in En | MEDLINE | ID: mdl-38799515
ABSTRACT
This case highlights the importance of considering tuberculosis as an underlying cause of gastrointestinal amyloidosis, even in patients previously treated for the infection. Clinicians should maintain a high index of suspicion for atypical presentations of amyloidosis, especially in individuals with chronic inflammation, enabling early diagnosis and tailored management for improved patient outcomes. Abstract Gastrointestinal amyloidosis is a rare condition often associated with chronic inflammation. We present a unique case of a 50-year-old female with a history of miliary tuberculosis who developed gastrointestinal amyloidosis. The patient exhibited chronic loose stools, weight loss, abdominal pain, and urinary incontinence symptoms. Diagnostic workup revealed characteristic findings of amyloidosis on biopsy. Despite treatment for tuberculosis, her symptoms persisted, highlighting the challenging nature of managing this condition. This case underscores the importance of considering tuberculosis as a potential cause of secondary amyloidosis in patients with ongoing symptoms of inflammation and infection. Early recognition and tailored management are crucial in optimizing patient outcomes.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Clin Case Rep Year: 2024 Document type: Article Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Clin Case Rep Year: 2024 Document type: Article Country of publication: Reino Unido