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Vasospasm and subsequent stroke from paraneoplastic syndrome in a pediatric patient with an intracranial mature teratoma: a case report.
Jenson, Amanda V; Rizvi, Ali Yunus; Reynolds, Rebecca A; Hartnett-Wright, Sara; Gellar, Thomas J; Stapleton, Stacie; Gonzalez-Gomez, Ignacio; Akbari, S Hassan A; Smyth, Matthew D.
Affiliation
  • Jenson AV; Division of Pediatric Neurosurgery, Johns Hopkins All Children's Hospital, St Petersburg, FL, USA. ajenson2@jh.edu.
  • Rizvi AY; School of Public Health, University of Michigan, Ann Arbor, MI, USA.
  • Reynolds RA; Division of Pediatric Neurosurgery, University of Iowa Stead Family Children's Hospital, Iowa City, IA, USA.
  • Hartnett-Wright S; Division of Pediatric Neurosurgery, Johns Hopkins All Children's Hospital, St Petersburg, FL, USA.
  • Gellar TJ; Division of Pediatric Neurology, Johns Hopkins All Children's Hospital, St Petersburg, FL, USA.
  • Stapleton S; Division of Pediatric Oncology, Johns Hopkins All Children's Hospital, St Petersburg, FL, USA.
  • Gonzalez-Gomez I; Division of Pediatric Pathology, Johns Hopkins All Children's Hospital, St Petersburg, FL, USA.
  • Akbari SHA; Division of Pediatric Neurosurgery, Johns Hopkins All Children's Hospital, St Petersburg, FL, USA.
  • Smyth MD; Division of Pediatric Neurosurgery, Johns Hopkins All Children's Hospital, St Petersburg, FL, USA.
Childs Nerv Syst ; 40(9): 2957-2960, 2024 Sep.
Article in En | MEDLINE | ID: mdl-38819669
ABSTRACT
Teratomas account for 18-20% of all intracranial germ cell tumors and mostly occur in the pineal region with only a few cases of pediatric sellar and suprasellar teratomas described in the literature. Here, we present a case of a child with an intracranial mature teratoma with pancreatic features causing vasospasm and subsequent stroke, found to be positive for CDKN2A-an independent variant associated with malignancy and small vessel disease leading to stroke.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Teratoma / Brain Neoplasms / Stroke / Vasospasm, Intracranial Limits: Child / Female / Humans / Male Language: En Journal: Childs Nerv Syst Journal subject: NEUROLOGIA / PEDIATRIA Year: 2024 Document type: Article Affiliation country: Estados Unidos Country of publication: Alemania

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Teratoma / Brain Neoplasms / Stroke / Vasospasm, Intracranial Limits: Child / Female / Humans / Male Language: En Journal: Childs Nerv Syst Journal subject: NEUROLOGIA / PEDIATRIA Year: 2024 Document type: Article Affiliation country: Estados Unidos Country of publication: Alemania