Generation of an iPSC line from a 79-year-old female patient diagnosed with sporadic Parkinson's disease.
Stem Cell Res
; 78: 103450, 2024 Aug.
Article
in En
| MEDLINE
| ID: mdl-38820865
ABSTRACT
Parkinson's disease is a common neurodegenerative disorder. Here we present a human induced pluripotent stem cells (iPSCs) derived from peripheral blood mononuclear cells (PBMCs) of a 79-year-old female patient diagnosed with sporadic Parkinson's disease using the sendai virus. Generated iPSCs maintain normal karyotype, exhibit pluripotent stem cell markers, and possess differentiation potential. The iPSCs allows for differentiation into various cell subtypes, providing conditions for the research of the pathogenesis and drug development of Parkinson's disease.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Parkinson Disease
/
Cell Differentiation
/
Induced Pluripotent Stem Cells
Limits:
Aged
/
Female
/
Humans
Language:
En
Journal:
Stem Cell Res
Year:
2024
Document type:
Article
Affiliation country:
China
Country of publication:
Reino Unido