Reaction-Kinetic Modeling of Photorespiration Using Modelbase.
Methods Mol Biol
; 2792: 223-240, 2024.
Article
in En
| MEDLINE
| ID: mdl-38861091
ABSTRACT
Plant science has become more and more complex. With the introduction of new experimental techniques and technologies, it is now possible to explore the fine details of plant metabolism. Besides steady-state measurements often applied in gas-exchange or metabolomic analyses, new approaches, e.g., based on 13C labeling, are now available to understand the changes in metabolic concentrations under fluctuating environmental conditions in the field or laboratory. To explore those transient phenomena of metabolite concentrations, kinetic models are a valuable tool. In this chapter, we describe ways to implement and build kinetic models of plant metabolism with the Python software package modelbase. As an example, we use a part of the photorespiratory pathway. Moreover, we show additional functionalities of modelbase that help to explore kinetic models and thus can reveal information about a biological system that is not easily accessible to experiments. In addition, we will point to extra information on the mathematical background of kinetic models to give an impetus for further self-study.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Plants
/
Software
/
Models, Biological
Language:
En
Journal:
Methods Mol Biol
Journal subject:
BIOLOGIA MOLECULAR
Year:
2024
Document type:
Article
Affiliation country:
Alemania
Country of publication:
Estados Unidos