Role of Endogenous Opioids in the Pathophysiology of Obesity and Eating Disorders.
Adv Neurobiol
; 35: 329-356, 2024.
Article
in En
| MEDLINE
| ID: mdl-38874731
ABSTRACT
This second chapter in our trilogy reviews and critically appraises the scientific evidence for the role of endogenous opioid system (EOS) activity in the onset and progression of both obesity and eating disorders. Defining features of normative eating and maladaptive eating behaviors are discussed as a foundation. We review the scientific literature pertaining to the predisposing risk factors and pathophysiology for obesity and eating disorders. Research targeting the association between obesity, disordered eating, and psychiatric comorbidities is reviewed. We conclude by discussing the involvement of endogenous opioids in neurobiological and behavior traits, and the clinical evidence for the role of the EOS in obesity and eating disorders.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Feeding and Eating Disorders
/
Opioid Peptides
/
Obesity
Limits:
Humans
Language:
En
Journal:
Adv Neurobiol
/
Advances in neurobiology (Internet)
Year:
2024
Document type:
Article
Affiliation country:
México
Country of publication:
Estados Unidos