Effective application of a direct-acting oral anticoagulants reversal agent in acute type A aortic dissection repair: A case report.
Asian Cardiovasc Thorac Ann
; 32(4): 213-214, 2024 May.
Article
in En
| MEDLINE
| ID: mdl-38884576
ABSTRACT
There are insufficient reports on the use of andexanet alfa in cardiac surgery. A 67-year-old man was diagnosed with type A aortic dissection and performed emergent surgery. His medical history included atrial fibrillation treated with Edoxaban. We performed total arch replacement. Despite administration of enough protamine, fresh frozen plasma, and platelet administration, controlling bleeding was difficult. Thus, Andexanet Alfa was initiated after CPB withdrawal. Surgical bleeding was dramatically controlled after its administration. There were no findings suggestive of an embolic event. In conclusion, administration of Andexanet Alfa is safe after cardiopulmonary bypass withdrawal.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Blood Vessel Prosthesis Implantation
/
Factor Xa Inhibitors
/
Aortic Dissection
Limits:
Aged
/
Humans
/
Male
Language:
En
Journal:
Asian Cardiovasc Thorac Ann
/
Asian cardiovasc. thoracic. ann
/
Asian cardiovascular & thoracic annals
Journal subject:
ANGIOLOGIA
/
CARDIOLOGIA
Year:
2024
Document type:
Article
Affiliation country:
Japón
Country of publication:
Reino Unido