A very complicated UTI: malakoplakia following E. coli urinary tract infection.
BMC Nephrol
; 25(1): 200, 2024 Jun 18.
Article
in En
| MEDLINE
| ID: mdl-38890600
ABSTRACT
Malakoplakia is a rare inflammatory disorder believed to result from a defect in macrophage phagocytic function triggering a granulomatous reaction. It can present with genitourinary, gastrointestinal, or cutaneous manifestations in immunocompromised or, less commonly, immunocompetent hosts. We describe a case of renal malakoplakia in a young, otherwise healthy patient presenting with nephromegaly and sepsis following an E. coli urinary tract infection. We discuss diagnosis and management, including antibiotic selection and the decision to pursue nephrectomy. This case highlights the potential for kidney recovery with prolonged antibiotic therapy in conjunction with adjunct immunomodulatory therapies and source control.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Urinary Tract Infections
/
Escherichia coli Infections
/
Malacoplakia
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
BMC Nephrol
Journal subject:
NEFROLOGIA
Year:
2024
Document type:
Article
Affiliation country:
Estados Unidos