Role of Anti-Müllerian Hormone in Male Reproduction and Sperm Motility.
Semin Reprod Med
; 42(1): 5-14, 2024 Mar.
Article
in En
| MEDLINE
| ID: mdl-38914117
ABSTRACT
Anti-Müllerian hormone (AMH) is secreted by Sertoli cells and is responsible for the regression of Müllerian ducts in the male fetus as part of the sexual differentiation process. Serum AMH concentrations are at their lowest levels in the first days after birth but increase after the first week, likely reflecting active Sertoli cell proliferation. AMH rises rapidly in concentration in boys during the first month, reaching a peak level at â¼6 months of age, and it remains high during childhood, then they will slowly decline during puberty, falling to low levels in adulthood. Serum AMH measurement is used by pediatric endocrinologist as a specific marker of immature Sertoli cell number and function during childhood. After puberty, AMH is released especially by the apical pole of the Sertoli cells toward the lumen of the seminiferous tubules, resulting in higher levels in the seminal plasma than in the serum. Recently, AMH has received increasing attention in research on male fertility-related disorders. This article reviews and summarizes the potential contribution of serum AMH measurement in different male fertility-related disorders.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sperm Motility
/
Anti-Mullerian Hormone
/
Infertility, Male
Limits:
Animals
/
Humans
/
Male
Language:
En
Journal:
Semin Reprod Med
Journal subject:
MEDICINA REPRODUTIVA
Year:
2024
Document type:
Article
Affiliation country:
Francia