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Boosting endogenous dopamine production: a novel therapeutic approach for Parkinson's disease.
Douma, Erik H; Smidt, Marten P; van der Heide, Lars P.
Affiliation
  • Douma EH; Parkinnova Therapeutics, Science Park 904, 1098 XH, Amsterdam, The Netherlands.
  • Smidt MP; Swammerdam Institute for Life Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands.
  • van der Heide LP; Swammerdam Institute for Life Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands. Electronic address: l.p.vanderheide@uva.nl.
Trends Mol Med ; 2024 Jun 25.
Article in En | MEDLINE | ID: mdl-38926032
ABSTRACT
Innovative therapeutic strategies are urgently needed for Parkinson's disease due to limited efficacy of current treatments and a weak therapeutic pipeline. In this forum article, we propose targeting tyrosine hydroxylase phosphorylation as a novel mechanism of action to address this critical need.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Trends Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2024 Document type: Article Affiliation country: Países Bajos Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Trends Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2024 Document type: Article Affiliation country: Países Bajos Country of publication: Reino Unido