[Structural design and evaluation of bone remodeling effect of fracture internal fixation implants with time-varying stiffness].
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
; 41(3): 595-603, 2024 Jun 25.
Article
in Zh
| MEDLINE
| ID: mdl-38932547
ABSTRACT
The stiffness of an ideal fracture internal fixation implant should have a time-varying performance, so that the fracture can generate reasonable mechanical stimulation at different healing stages, and biodegradable materials meet this performance. A topology optimization design method for composite structures of fracture internal fixation implants with time-varying stiffness is proposed, considering the time-dependent degradation process of materials. Using relative density and degradation residual rate to describe the distribution and degradation state of two materials with different degradation rates and elastic modulus, a coupled mathematical model of degradation simulation mechanical analysis was established. Biomaterial composite structures were designed based on variable density method to exhibit time-varying stiffness characteristics. Taking the bone plate used for the treatment of tibial fractures as an example, a composite structure bone plate with time-varying stiffness characteristics was designed using the proposed method. The optimization results showed that material 1 with high stiffness formed a columnar support structure, while material 2 with low stiffness was distributed at the degradation boundary and inside. Using a bone remodeling simulation model, the optimized bone plates were evaluated. After 11 months of remodeling, the average elastic modulus of callus using degradable time-varying stiffness plates, titanium alloy plates, and stainless steel plates were 8 634 MPa, 8 521 MPa, and 8 412 MPa, respectively, indicating that the use of degradable time-varying stiffness plates would result in better remodeling effects on the callus.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tibial Fractures
/
Titanium
/
Bone Plates
/
Bone Remodeling
/
Elastic Modulus
/
Fracture Fixation, Internal
Limits:
Humans
Language:
Zh
Journal:
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
Journal subject:
ENGENHARIA BIOMEDICA
Year:
2024
Document type:
Article
Country of publication:
China