Analysis of Toxicity of Recombinant Pneumolysin from Streptococcus pneumoniae.
Bull Exp Biol Med
; 177(1): 137-139, 2024 May.
Article
in En
| MEDLINE
| ID: mdl-38960960
ABSTRACT
We studied toxicity of recombinant Streptococcus pneumoniae pneumolysin protein in experiments on mice and its cytopathogenic effect on cultures of Vero green monkey kidney cells and human lung carcinoma A549 cells in vitro. In vivo and in vitro experiments proved the absence of compromised toxicity and direct cytopathogenic action of the recombinant protein.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Streptococcus pneumoniae
/
Streptolysins
/
Bacterial Proteins
/
Recombinant Proteins
Limits:
Animals
/
Humans
Language:
En
Journal:
Bull Exp Biol Med
Year:
2024
Document type:
Article
Affiliation country:
Rusia
Publication country:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA