Biomaterials as a new option for treating sensorineural hearing loss.
Biomater Sci
; 12(16): 4006-4023, 2024 Aug 06.
Article
in En
| MEDLINE
| ID: mdl-38979939
ABSTRACT
Sensorineural hearing loss (SNHL) usually involves damage to complex auditory pathways such as inner ear cells and auditory nerves. The highly intricate and nuanced characteristics of these cells render their repair and regeneration extremely challenging, making it difficult to restore hearing to normal levels once it has been compromised. The effectiveness of traditional drugs is so minimal that they provide little help with the treatment. Fortunately, extensive experiments have demonstrated that combining biomaterials with conventional techniques significantly enhances drug effectiveness. This article reviews the research progress of biomaterials in protecting hair cells and the auditory nerve, repairing genes related to hearing, and developing artificial cochlear materials. By organizing the knowledge presented in this article, perhaps new insights can be provided for the clinical management of SNHL.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Biocompatible Materials
/
Hearing Loss, Sensorineural
Limits:
Animals
/
Humans
Language:
En
Journal:
Biomater Sci
Year:
2024
Document type:
Article
Affiliation country:
China