Research Progress of Hydrogel Microneedles in Wound Management.
ACS Biomater Sci Eng
; 10(8): 4771-4790, 2024 Aug 12.
Article
in En
| MEDLINE
| ID: mdl-38982708
ABSTRACT
Microneedles are a novel drug delivery system that offers advantages such as safety, painlessness, minimally invasive administration, simplicity of use, and controllable drug delivery. As a type of polymer microneedle with a three-dimensional network structure, hydrogel microneedles (HMNs) possess excellent biocompatibility and biodegradability and encapsulate various therapeutic drugs while maintaining drug activity, thus attracting significant attention. Recently, they have been widely employed to promote wound healing and have demonstrated favorable therapeutic effects. Although there are reviews about HMNs, few of them focus on wound management. Herein, we present a comprehensive overview of the design and preparation methods of HMNs, with a particular emphasis on their application status in wound healing, including acute wound healing, infected wound healing, diabetic wound healing, and scarless wound healing. Finally, we examine the advantages and limitations of HMNs in wound management and provide suggestions for future research directions.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Wound Healing
/
Drug Delivery Systems
/
Hydrogels
/
Needles
Limits:
Animals
/
Humans
Language:
En
Journal:
ACS Biomater Sci Eng
Year:
2024
Document type:
Article
Affiliation country:
China