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Vitamin D binding protein in psychiatric and neurological disorders: Implications for diagnosis and treatment.
Li, Ling; Han, Bing; Kong, Yan; Zhang, Gaojia; Zhang, Zhijun.
Affiliation
  • Li L; Research Institution of Neuropsychiatry, School of Medicine, Southeast University, Nanjing, Jiangsu 210009, China.
  • Han B; Department of Neurology, Affiliated Zhongda Hospital, Nanjing, Jiangsu 210009, China.
  • Kong Y; Department of Pharmacology, Jiangsu Provincial Key Laboratory of Critical Care Medicine, School of Medicine, Southeast University, Nanjing, Jiangsu 210009, China.
  • Zhang G; Department of Biochemistry and Molecular Biology, School of Medicine, Southeast University, Nanjing, Jiangsu 210009, China.
  • Zhang Z; Research Institution of Neuropsychiatry, School of Medicine, Southeast University, Nanjing, Jiangsu 210009, China.
Genes Dis ; 11(5): 101309, 2024 Sep.
Article in En | MEDLINE | ID: mdl-38983447
ABSTRACT
Vitamin D binding protein (VDBP) serves as a key transporter protein responsible for binding and delivering vitamin D and its metabolites to target organs. VDBP plays a crucial part in the inflammatory reaction following tissue damage and is engaged in actin degradation. Recent research has shed light on its potential role in various diseases, leading to a growing interest in understanding the implications of VDBP in psychiatric and neurological disorders. The purpose of this review was to provide a summary of the existing understanding regarding the involvement of VDBP in neurological and psychiatric disorders. By examining the intricate interplay between VDBP and these disorders, this review contributes to a deeper understanding of underlying mechanisms and potential therapeutic avenues. Insights gained from the study of VDBP could pave the way for novel strategies in the diagnosis, prognosis, and treatment of psychiatric and neurological disorders.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Genes Dis Year: 2024 Document type: Article Affiliation country: China Country of publication: Países Bajos

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Genes Dis Year: 2024 Document type: Article Affiliation country: China Country of publication: Países Bajos