Benzisoselenazoles as Selenophenolate Anion Surrogates for the Formation of Carbon-Selenium Bonds via the Selena-Kemp Reaction.
J Org Chem
; 89(15): 10462-10466, 2024 Aug 02.
Article
in En
| MEDLINE
| ID: mdl-39042117
ABSTRACT
The in situ base-promoted generation of unstable selenophenolate anions from 1,2-benzisoselenazoles via a variant of the Kemp elimination has been developed. 2-Cyano-substituted selenophenolate anions obtained by this methodology were engaged in nucleophilic substitution, aromatic nucleophilic substitution, and Pd-catalyzed cross-coupling reactions to give functionalized arylalkyl and diaryl selenides in moderate to excellent yields.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
J Org Chem
Year:
2024
Document type:
Article
Affiliation country:
Francia