Eight new dammarane-type triterpenoid saponins from Gynostemma pentaphyllum.
Nat Prod Res
; : 1-9, 2024 Jul 31.
Article
in En
| MEDLINE
| ID: mdl-39086211
ABSTRACT
Phytochemical investigation of Gynostemma pentaphyllum led to the purification of five novel dammarane-type triterpene isolates, gypenosides B1 - B5 (1-5). Their structures were determined through comprehensive 1D and 2D NMR spectroscopic analyses and HRESIMS data. Of note, 1-3 are inseparable mixtures of epimers due to their unstable nature, and a total of eight dammarane-type triterpene saponins were identified. Additionally, the protective activities of these new compounds against PC12 cell injury induced by hypoxia were evaluated.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Nat Prod Res
Year:
2024
Document type:
Article
Affiliation country:
China