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In situ deposition of nanobodies by an engineered commensal microbe promotes survival in a mouse model of enterohemorrhagic E. coli.
Srivastava, Rajkamal; González-Prieto, Coral; Lynch, Jason P; Muscolo, Michele; Lin, Catherine Y; Brown, Markus A; Lemos, Luisa; Shrestha, Anishma; Osburne, Marcia S; Leong, John M; Lesser, Cammie F.
Affiliation
  • Srivastava R; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, MA, 02115, USA.
  • González-Prieto C; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, 02115, USA.
  • Lynch JP; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, MA, 02115, USA.
  • Muscolo M; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, 02115, USA.
  • Lin CY; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, MA, 02115, USA.
  • Brown MA; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, 02115, USA.
  • Lemos L; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, MA, 02115, USA.
  • Shrestha A; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, MA, 02115, USA.
  • Osburne MS; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, MA, 02115, USA.
  • Leong JM; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, 02115, USA.
  • Lesser CF; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, MA, 02115, USA.
bioRxiv ; 2024 Jul 30.
Article in En | MEDLINE | ID: mdl-39131305
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2024 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2024 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos