[First detection of the SLC2A9:p.C188F gene defect in a German Hunting Terrier with ammonium urate urolithiasis]. / Erstmaliger Nachweis des SLC2A9:p.C188F Gendefekts bei einem Deutschen Jagdterrier mit Ammoniumurat-Urolithiasis.
Tierarztl Prax Ausg K Kleintiere Heimtiere
; 52(4): 232-237, 2024 Aug.
Article
in De
| MEDLINE
| ID: mdl-39173651
ABSTRACT
A 1,5-year-old intact male German Hunting Terrier was initially presented 2018 with hematuria. An abdominal ultrasound revealed multiple hyperechogenic structures in the urinary bladder. A urinalysis indicated severe crystalluria (ammonium urate or xanthine). Following cystotomy and urinary calculus analysis, ammonium urate urolithiasis was diagnosed in 2019. The patient was tested homozygous at the SLC2A9p.C188F variant, which results in severe hyperuricemia and hyperuricosuria. This case report presents the first incidence of the SLC2A9p.C188F gene variant being detected in a German Hunting Terrier. Veterinary practitioners are encouraged to consider the possibility of this gene defect presenting in breeds beyond the Dalmatian.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Uric Acid
/
Dog Diseases
/
Glucose Transport Proteins, Facilitative
/
Urolithiasis
Limits:
Animals
Language:
De
Journal:
Tierarztl Prax Ausg K Kleintiere Heimtiere
Journal subject:
MEDICINA VETERINARIA
Year:
2024
Document type:
Article
Country of publication:
Alemania