Correlation between the metabolic score for visceral fat and chronic obstructive pulmonary disease among middle-aged and elderly American population.
Eur Rev Med Pharmacol Sci
; 28(15): 4046-4059, 2024 Aug.
Article
in En
| MEDLINE
| ID: mdl-39194200
ABSTRACT
OBJECTIVE:
A metabolism score for visceral fat (METS-VF) is an innovative method to access abdominal fat and visceral fat. So far, the relationship between the METS-VF index and chronic obstructive pulmonary disease (COPD) has remained unclear. We investigated the relationship between the METS-VF index and COPD prevalence utilizing data from the National Health and Nutrition Examination Survey (NHANES) 2007-2018. PATIENTS ANDMETHODS:
A binary logistic regression analysis was performed using NHANES 2007-2018 data to assess the relationship between the METS-VF index and COPD prevalence. The relationship was verified by fitted smooth curves, generalized additive models, threshold effect analyses, subgroup analyses, and sensitivity analyses.RESULTS:
In total, 7,680 subjects were recruited for the study, including 772 self-reported having COPD. The METS-VF index was positively related to COPD prevalence when adjusted for all covariates. The METS-VF index was classified by quartiles, and participants who scored highest on METS-VF were at a greater risk of COPD than those who scored lowest. According to a threshold effect analysis, the METS-VF index was negatively correlated with COPD prevalence with a METS-VF index <7.00, without statistical significance. Once the METS-VF index exceeded 7.00, there was a robust positive correlation between the METS-VF index and COPD prevalence. In the analysis of subgroups, the METS-VF index was positively correlated with COPD prevalence among subjects who were male, aged 40-59, and without asthma or hypertension. The results were robust in sensitivity analyses. METS-VF showed a significantly better diagnostic value for COPD than Body Mass Index (BMI).CONCLUSIONS:
The METS-VF index has a non-linear and positive correlation with COPD prevalence in the middle-aged and elderly American population.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Nutrition Surveys
/
Pulmonary Disease, Chronic Obstructive
/
Intra-Abdominal Fat
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
America do norte
Language:
En
Journal:
Eur Rev Med Pharmacol Sci
Journal subject:
FARMACOLOGIA
/
TOXICOLOGIA
Year:
2024
Document type:
Article
Affiliation country:
China
Publication country:
IT
/
ITALIA
/
ITALY
/
ITÁLIA