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A novel antidepressant homogeneous polysaccharide YLP-1 from Millettia pulchra ameliorates tryptophan metabolism and SCFAs through modulating gut microbiota.
Yu, Meng; Cai, Cong-Cong; Huang, Yun-Feng; Zhu, Yin-Di; Luo, Xin-Yao; Kong, Xin-Yu; Zhang, Wen-Ting; Li, Hui-Jun; Fang, Jing-Xian; Zou, Zhong-Mei.
Affiliation
  • Yu M; The State Key Laboratory of Basis and New Drug Development of Natural and Nuclear Drugs, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China.
  • Cai CC; The State Key Laboratory of Basis and New Drug Development of Natural and Nuclear Drugs, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China.
  • Huang YF; Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Guangxi Institute of Traditional Medicine and Pharmaceutical Science, Nanning, 530022, China.
  • Zhu YD; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
  • Luo XY; The State Key Laboratory of Basis and New Drug Development of Natural and Nuclear Drugs, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China.
  • Kong XY; The State Key Laboratory of Basis and New Drug Development of Natural and Nuclear Drugs, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China.
  • Zhang WT; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
  • Li HJ; Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
  • Fang JX; Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
  • Zou ZM; The State Key Laboratory of Basis and New Drug Development of Natural and Nuclear Drugs, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China. Electronic address: zmzou@implad.ac.cn.
Carbohydr Polym ; 344: 122527, 2024 Nov 15.
Article in En | MEDLINE | ID: mdl-39218534
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides / Tryptophan / Millettia / Fatty Acids, Volatile / Gastrointestinal Microbiome / Antidepressive Agents Limits: Animals Language: En Journal: Carbohydr Polym Year: 2024 Document type: Article Affiliation country: China Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides / Tryptophan / Millettia / Fatty Acids, Volatile / Gastrointestinal Microbiome / Antidepressive Agents Limits: Animals Language: En Journal: Carbohydr Polym Year: 2024 Document type: Article Affiliation country: China Country of publication: Reino Unido