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Genome-wide CRISPR/Cas9 library screening identified OGDH as a regulator of disease progress and resistance to decitabine in myelodysplastic neoplasm by reprogramming glutamine metabolism.
Xu, Xiaoyan; Qi, Jiaqian; Wang, Hong; Zhang, Ziyan; Pan, Tingting; Li, Xueqian; Yang, Jingyi; Han, Haohao; Guo, Mengting; Zhou, Meng; Cai, Chengsen; Tang, Yaqiong; Hou, Qixiu; Chen, Suning; Wu, Depei; Han, Yue.
Affiliation
  • Xu X; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Qi J; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.
  • Wang H; Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China.
  • Zhang Z; State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, China.
  • Pan T; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Li X; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.
  • Yang J; Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China.
  • Han H; State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, China.
  • Guo M; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Zhou M; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.
  • Cai C; Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China.
  • Tang Y; State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, China.
  • Hou Q; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Chen S; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.
  • Wu D; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Han Y; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.
Leukemia ; 2024 Sep 03.
Article in En | MEDLINE | ID: mdl-39227691
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2024 Document type: Article Affiliation country: China Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2024 Document type: Article Affiliation country: China Country of publication: Reino Unido