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Diffuse Large B-Cell Lymphoma in a Cynomolgus Monkey.
Li, Heling; Zhang, Long; Chen, Zhigang; Zong, Faliang; Tian, Baohong; Chen, Xinglong; Liu, Deli; Ning, Qing; Wang, Hong.
Affiliation
  • Li H; State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China.
  • Zhang L; Yunnan Key Laboratory of Primate Biomedical Research, Kunming, China.
  • Chen Z; Kunming Biomed International Ltd., Kunming, China.
  • Zong F; State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China.
  • Tian B; Yunnan Key Laboratory of Primate Biomedical Research, Kunming, China.
  • Chen X; Yunnan Key Laboratory of Primate Biomedical Research, Kunming, China.
  • Liu D; State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China.
  • Ning Q; State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China.
  • Wang H; Yunnan Key Laboratory of Primate Biomedical Research, Kunming, China.
J Med Primatol ; 53(5): e12734, 2024 Oct.
Article in En | MEDLINE | ID: mdl-39245882
ABSTRACT
A captive 17-year-old male cynomolgus monkey (Macaca fascicularis) developed diffuse large B-cell lymphoma (DLBCL). This was the first report of DLBCL presenting with a mandible mass and violation of the paranasal sinus in a cynomolgus monkey. The neoplasm showed marked microscopical malignant aspects. Immunohistochemical staining showed strong positive expression of CD20. These features may contribute to the diagnosis and therapeutics of DLBCL in NHPs.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphoma, Large B-Cell, Diffuse / Macaca fascicularis / Monkey Diseases Limits: Animals Language: En Journal: J Med Primatol / J. med. primatol / Journal of medical primatology Year: 2024 Document type: Article Affiliation country: China Country of publication: Dinamarca
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphoma, Large B-Cell, Diffuse / Macaca fascicularis / Monkey Diseases Limits: Animals Language: En Journal: J Med Primatol / J. med. primatol / Journal of medical primatology Year: 2024 Document type: Article Affiliation country: China Country of publication: Dinamarca