Role of Posaconazole Drug in the Treatment of Invasive Fungal Disease: A Review.
Infect Disord Drug Targets
; 2024 Sep 11.
Article
in En
| MEDLINE
| ID: mdl-39313878
ABSTRACT
Posaconazole is an antifungal medication used primarily to treat invasive fungal in-fections caused by various organisms, such as Aspergillus, Candida, and certain molds. It be-longs to the class of drugs known as triazole antifungals. Clinical studies have reported posaconazole to be effective in treating various invasive fungal infections, especially in patients who are immunocompromised, such as those with weakened immune systems due to conditions like HIV/AIDS, undergoing chemotherapy, or having received an organ transplant. It has ef-fectively treated invasive candidiasis, aspergillosis, zygomycosis, and other serious fungal in-fections. The effectiveness of the drug varies based on factors, such as the type of infection, the patient's immune status, and the site of infection. This review describes the types of infection, the drug's safety profile, the development of resistance to posaconazole, and strategies to man-age or prevent resistance.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Infect Disord Drug Targets
Journal subject:
DOENCAS TRANSMISSIVEIS
/
TERAPIA POR MEDICAMENTOS
Year:
2024
Document type:
Article
Affiliation country:
India
Country of publication:
Emiratos Árabes Unidos