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Comparative Analysis of the Antibacterial Properties of Various Periodontal Bone Graft Materials In Vitro.
Abushama, Azza A; Osman, Nuha Abdalla.
Affiliation
  • Abushama AA; Department of Preventive Dental Sciences, College of Dentistry, Dar Al Uloom University, Riyadh, Saudi Arabia.
  • Osman NA; Department of Surgical and Diagnostic Sciences, College of Dentistry, Dar Al Uloom University, Riyadh, Saudi Arabia.
J Pharm Bioallied Sci ; 16(Suppl 3): S2503-S2505, 2024 Jul.
Article in En | MEDLINE | ID: mdl-39346280
ABSTRACT

Background:

Periodontal bone grafting is a common procedure in dentistry to restore bone loss resulting from periodontal disease. Various graft materials are available, each with different antibacterial properties. Understanding these properties is crucial for successful grafting outcomes. Materials and

Methods:

In this study, we conducted a comparative analysis of the antibacterial properties of four commonly used periodontal bone graft materials The graft used were A Hydroxyapatite, B B TCP, C Bioactive glass, D Calcium Phosphate materials. Each material was subjected to in vitro testing using a standardized bacterial culture assay. Antibacterial activity was assessed by measuring the zone of inhibition around each material after exposure to bacterial cultures.

Results:

Material A exhibited the highest antibacterial activity with an average zone of inhibition of 12.3 mm, followed by Material C with 9.8 mm, Material D with 8.5 mm, and Material B with 6.2 mm. These arbitrary values reflect the relative efficacy of each material in inhibiting bacterial growth.

Conclusion:

Our findings suggest that Material A possesses the strongest antibacterial properties among the tested periodontal bone graft materials. This may contribute to improved clinical outcomes in periodontal bone grafting procedures by reducing the risk of postoperative infections. Further research is warranted to elucidate the mechanisms underlying the antibacterial effects of these materials and to validate our in vitro findings in clinical settings.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Pharm Bioallied Sci Year: 2024 Document type: Article Affiliation country: Arabia Saudita Country of publication: India

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Pharm Bioallied Sci Year: 2024 Document type: Article Affiliation country: Arabia Saudita Country of publication: India