Pharmacokinetics of ceftazidime in newborn infants.
Antimicrob Agents Chemother
; 26(4): 583-4, 1984 Oct.
Article
in En
| MEDLINE
| ID: mdl-6393862
ABSTRACT
Doses of 50 mg of ceftazidime per kg were administered intravenously to 29 newborn infants every 8 or 12 h for 3 to 5 days. Mean peak concentrations in plasma ranged from 102 to 124 micrograms/ml. Mean elimination half-life values ranged from 2.9 to 6.7 h and varied inversely with gestational age and plasma clearances. Peak and trough plasma bactericidal titers against an Escherichia coli and a group B streptococcus strain were at least 116 and 132, respectively.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ceftazidime
Limits:
Humans
/
Infant
/
Newborn
Language:
En
Journal:
Antimicrob Agents Chemother
Year:
1984
Document type:
Article