Chrysiasis resulting from gold therapy in rheumatoid arthritis: identification of gold by x-ray microanalysis.
Mayo Clin Proc
; 57(12): 773-7, 1982 Dec.
Article
in En
| MEDLINE
| ID: mdl-6815384
ABSTRACT
A patient with blue-gray discoloration of the skin of her face, neck, and hands is described. She was a patient with rheumatoid arthritis who had received a large total cumulative dose of gold. Light microscopy of skin biopsy tissue from the forehead revealed deposits of heavy metal in macrophages. On electron microscopy, the particles were found in the lysosomes of the cell. X-ray microanalysis confirmed the presence of gold. This condition, which is called chrysiasis, may be incorrectly diagnosed as cyanosis.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pigmentation Disorders
/
Arthritis, Rheumatoid
/
Aurothioglucose
/
Gold
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Female
/
Humans
/
Middle aged
Language:
En
Journal:
Mayo Clin Proc
Year:
1982
Document type:
Article