Single- and multiple-dose-response relationships of beta-carotene in cystic fibrosis.
J Pediatr
; 127(3): 491-4, 1995 Sep.
Article
in En
| MEDLINE
| ID: mdl-7658286
ABSTRACT
Concentrations of carotenoids are low in patients with cystic fibrosis (CF) and are associated with essential fatty acid deficiency and increased markers of inflammation. We conducted single- and multiple-dose studies of beta-carotene supplementation in patients with CF. Dose-proportional increases in beta-carotene concentrations were found, although clearance was independent of dose. Large doses of beta-carotene were necessary to achieve normal plasma levels.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Carotenoids
/
Adjuvants, Immunologic
/
Cystic Fibrosis
Type of study:
Clinical_trials
/
Diagnostic_studies
Limits:
Adult
/
Child
/
Female
/
Humans
/
Male
Language:
En
Journal:
J Pediatr
Year:
1995
Document type:
Article
Affiliation country:
Estados Unidos
Publication country:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA