Localization of the human interferon-induced, ds-RNA activated p68 kinase gene (PRKR) to chromosome 2p21-p22.
Genomics
; 16(3): 768-70, 1993 Jun.
Article
in En
| MEDLINE
| ID: mdl-7686884
ABSTRACT
The interferon-induced dsRNA-activated protein kinase (PRKR) belongs to a subclass of serine/threonine kinases, involved in the regulation of protein synthesis by phosphorylation of the alpha subunit of initiation factor eIF2. Somatic cell hybrids segregating human chromosomes were used to assign this kinase to human chromosome 2. Fluorescence in situ hybridization confirmed this assignment and further localized the gene (PRKR) to the boundary region of bands p21 and 22.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Chromosomes, Human, Pair 2
/
Protein Serine-Threonine Kinases
Limits:
Humans
Language:
En
Journal:
Genomics
Journal subject:
GENETICA
Year:
1993
Document type:
Article
Affiliation country:
Canadá