The gene encoding a new mitogenic factor in a Streptococcus pyogenes strain is distributed only in group A streptococci.
Infect Immun
; 62(9): 4000-4, 1994 Sep.
Article
in En
| MEDLINE
| ID: mdl-8063419
ABSTRACT
We recently cloned a gene encoding a new mitogenic factor (MF) from Streptococcus pyogenes NY-5. In the present study, we determined the distribution of this MF gene (mf) by PCR based upon its sequence. Of 371 streptococcal group A strains isolated from clinical specimens, 370 (99.7%) were positive for mf. The strain that was negative for the MF gene was also negative for the streptolysin O gene (slo). Some streptococcal strains belonging to groups C and G were negative for mf but positive for slo. Group B strains were negative for both. Furthermore, we examined the presence of mf in 54 strains belonging to 28 families and found mf only in group A streptococci. These results indicate that mf is distributed specifically in group A streptococci and the presence of mf in clinical samples strongly suggests infection with group A streptococci.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bacterial Proteins
/
Genes, Bacterial
/
Mitogens
Language:
En
Journal:
Infect Immun
Year:
1994
Document type:
Article
Affiliation country:
Japón