Inert placebo versus active medication. Patient blindability in clinical pharmacological trials.
J Nerv Ment Dis
; 182(9): 485-7, 1994 Sep.
Article
in En
| MEDLINE
| ID: mdl-8083675
ABSTRACT
Patient blindability was examined in clinical, psychopharmacological, double-blind, placebo-controlled trials involving medications for obsessive-compulsive disorder and major depression. Based on the presence of clinical improvement and side effects, patients were able to determine correctly whether they took medication versus placebo. On the basis of these preliminary findings, the authors question the blindability of patients in clinical trials. Implications for the continued use of double-blind, placebo-controlled trials are discussed.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Placebos
/
Clinical Trials as Topic
/
Depressive Disorder
/
Obsessive-Compulsive Disorder
Type of study:
Clinical_trials
Limits:
Humans
Language:
En
Journal:
J Nerv Ment Dis
Year:
1994
Document type:
Article