Cyclosporin A inhibits T cell receptor-induced interleukin-2 synthesis of human T lymphocytes by selectively preventing a transmembrane signal transduction pathway leading to sustained activation of a protein kinase C isoenzyme, protein kinase C-beta.
Eur J Immunol
; 23(12): 3072-81, 1993 Dec.
Article
in En
| MEDLINE
| ID: mdl-8258320
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Protein Kinase C
/
T-Lymphocytes
/
Signal Transduction
/
Interleukin-2
/
Cyclosporine
/
Isoenzymes
Limits:
Animals
/
Humans
Language:
En
Journal:
Eur J Immunol
Year:
1993
Document type:
Article
Country of publication:
Alemania