[Comparative study of 20% marine salt and 20% NaCl on circulatory dynamics during hemorrhagic shock in dogs].
Masui
; 43(1): 70-7, 1994 Jan.
Article
in Ja
| MEDLINE
| ID: mdl-8309059
ABSTRACT
This study was conducted to investigate the effect of 20% marine salt as compared with 20% NaCl solution, on the circulatory dynamics in hemorrhagic shock using mongrel dogs. Ten mongrel dogs were randomly divided into two groups. One treated with 20% marine salt, and the other treated with 20% NaCl. Modified Wigger's method was used to induce hemorrhagic shock. Hypotension was kept at 45 mmHg for 45 minutes and then 1.5 ml.kg-1 of 20% marine salt or 20% NaCl was injected intravenously in bolus. Twenty percent marine salt reduced total peripheral resistance and increased cardiac output with statistically significant difference compared with 20% NaCl. There were increases in MAP, PAP and PWP without statistic differences between the two groups. These results suggest that 20% marine salt, including various trace elements, is superior to 20% NaCl in improving cardiac output and TPR during hemorrhagic shock.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Shock, Hemorrhagic
/
Sodium Chloride
/
Hemodynamics
Limits:
Animals
Language:
Ja
Journal:
Masui
Year:
1994
Document type:
Article