Unexpected presence of neurofilaments in axon-bearing horizontal cells of the mammalian retina.
J Neurosci
; 13(9): 4091-100, 1993 Sep.
Article
in En
| MEDLINE
| ID: mdl-8366362
ABSTRACT
In several mammals only one of the two types of retinal horizontal cell, the axonless A-type, appears to express neurofilaments. Neurofilament immunostaining of rodent retinas reveals a horizontal cell plexus that has previously been interpreted as belonging to A-type cells. Our intracellular Lucifer yellow injections strongly suggest that there are no A-type horizontal cells in rat and gerbil. Counterstaining of dye-injected cellular structures with a neurofilament antibody directly shows that the axon terminal systems of the axon-bearing B-type horizontal cells contain neurofilaments. These unexpected findings explain and reinterpret the neurofilament plexus in rodent retinas. In contrast, Lucifer yellow injections in guinea pig retina reveal both A- and B-type horizontal cells, showing that horizontal cell types are not uniform among rodents. In the guinea pig retina both A-type cells and B-type axon terminal systems contain neurofilaments.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Retina
/
Axons
/
Intermediate Filaments
/
Neurofilament Proteins
/
Neurons
Limits:
Animals
Language:
En
Journal:
J Neurosci
Year:
1993
Document type:
Article
Affiliation country:
Alemania